期刊语言：英语

出版地区：美国

万维提示

1、投稿方式：在线投稿。

2、期刊网址：

https://www.spandidos-publications.com/ijmm/

3、投稿网址：

https://www.spandidos-publications.com/login

4、官网邮箱：ijmm@spandidos-publications.com

5、期刊刊期：月刊，一年出版12期。

2021年10月25日星期一

投稿须知【官网信息】

Information for authors

International Journal of Molecular Medicine

Submission guidelines

The principal aim of Spandidos Publications is to publish promptly original works of high quality in English.

Manuscripts will be considered on the understanding that they report original work, or are review articles summarizing and interpreting progress in a thematic area and are not under consideration for publication by another journal.

Manuscripts should be written in clear, concise English and should contain all essential data in order to make the presentation clear and the results of the study replicable.

Authors who are not native speakers of English but would like to improve the English to ensure the meaning is clear can make use of the English Language Editing service offered by Spandidos Publications by accessing the following link.

All material submitted will be subject to review by appropriate referees selected by the Editorial Office and will be examined to detect inappropriate use of previously published material without attribution.

Spandidos Publications utilizes iThenticate to screen submitted manuscripts against published studies and other relevant sources. iThenticate may also be utilized by authors to screen a manuscript prior to submission.

Figures submitted will be subject to checks using the MOTUIN image authenticity detector.

The Editors reserve the right to improve the grammar and style of manuscripts.

The corresponding author is responsible for the submission on behalf of all authors.

Prior to submitting your manuscript, please ensure that it has been prepared according to the guidelines below.

1. Submission method

Manuscripts may be submitted only by using the online submission system accessible via our website. Create a user account, log in and follow the onscreen directions.

2. Cover letter

Summarize briefly the important points of the submitted work including a brief description of the study to be submitted, that it is an original study presenting novel work, that it has not been previously submitted to or accepted by any other journal, that is has been approved by all authors, that ethics approval and written informed consent have been obtained, and explain whether any author has a conflict of interest.

3. Format of articles and reviews

3.1 General style

Times New Roman. Font size 12. Spacing 1.5. Alignment Justified.

Use a single tab on the first line of each new paragraph.

Do not use page breaks or multiple returns between sections (one section should directly follow the previous one on the page).

Do not insert page numbers or line numbers.

Sub-titles and general headings should be presented in lower case letters (not capitals).

Use British English or American English spellings throughout your manuscript, but not both.

3.2 Manuscripts

The first page should include:

The title of the manuscript in sentence case. No abbreviations other than gene names or in common use.

Full names and full postal addresses, but not including street names, of all authors and ORCID if desired.

Affiliations of the authors indicated by numbers (not symbols).

Equal contribution, if applicable, indicated by asterisk.

Name, full postal address, including street number and name, and e-mail address of the corresponding author(s).

Abbreviations, if relevant.

Key words (5 – 10).

Running title preceded by the first author’s name (maximum 100 characters with spaces, including the author’s name). For example: PEARSON et al: REGULATION OF HER2 EXPRESSION BY NASCENT GROWTH FACTORS..

Manuscripts reporting experimental results must be divided into the following sections:

Abstract. This section should have 150‐300 words, be continuous (not structured) and without reference numbers. Abbreviations that appear once only, should be defined in full, with the exception of gene names. If abbreviations appear more than once, the definition should be provided once, and then subsequently used throughout the Abstract.

Introduction. The information in this section should always be referenced.

Materials and methods

This section should include sufficient technical information to allow the experiments to be repeated. This implies that a full description of all the experiments described in Results and presented in the Figures/Tables is expected in this section. For each experiment, all steps (e.g., DNA and protein extraction, quantification, cloning, PCR and microscopy) need to be mentioned, along with instruments the analyses were performed on, reagents and methods (e.g., BCA method for protein quantification, ΔΔCq method for qPCR), and relevant citations.

For steps performed with commercialized kits, provide the full name of the kit, along with the full name of the supplier, and state whether the protocol of the manufacturer was followed or explain any modifications made to the standard protocol. For PCRs, provide name of the kit used, the 5’-3’ sequence of the primers, final concentration of all reagents in the reaction and cycling conditions. Carefully review your text to ensure that the type of PCR, quantitative or semi-quantitative, is clearly explained. If the PCR is performed using cDNA synthesized from RNA samples by reverse transcription (RT), make sure that all steps are described, and refer to the method as RT-PCR or, if quantitative, as RT-qPCR. In relative quantification, ΔΔCt is referred to as ΔΔCq. When using the ΔΔCq method, this must be referenced. One suitable reference is: Livak and Schmittgen: Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCq method. Methods 25: 402-408, 2001.

Manufacturers/suppliers/software details need to be provided for all reagents used (including chemicals), instruments (e.g. thermal cyclers, microscopes) and software, ideally accompanied by the c orresponding kit number/model/version. For antibodies, include the type (monoclonal/polyclonal), species in which they were raised and targeted species (e.g., mouse anti-human), explain any antigen retrieval steps, mention the dilution used, and state the catalogue number and supplier. Please also state the temperature and duration of incubation. For centrifugation steps, provide centrifugal force units in x g rather than revolutions per minute (rpm).

For bioinformatic analyses: state the software used along with the relevant citation, unless the software is not published, in which case a website link can be provided. For microarray/RNA sequences, data downloaded from GEO or other databases, this needs to be clarified in the text, along with the corresponding accession number of the dataset. The use of software should be described with regards to the parameters (default, study-specific) and the applied thresholds; please explicitly name the parameters, e.g. ‘association value’ or ‘false-positive rate’. For all software analysis of data from public databases, cite the database (along with date of access for databases as these are constantly updated), and species (e.g., human). If Figures/Tables contain data from a public database (e.g., Gene Ontology/KEGG), cite the source in the legend/title explicitly. For publically available sequences, provide the accession number.

The source of material used and relevant ethical framework for all experiments should be clearly identified (ethics approval and/or written informed consent). For tissues, explain how these were collected, handled and stored, and where they were from. For bacterial strains or cells, provide the name and supplier. For studies on humans, a minimum of information is required: number of subjects, age range, gender ratio, health status, matching between controls and disease patients with regards to the above parameters. Please note that ‘normal’ should be avoided for controls; rather, the precise health status needs to be described, e.g., ‘healthy’, or ‘individuals with no recorded tumor complication’. For manuscripts presenting studies on humans and animals, see 3.8 below.

For statistical analyses: when statistical analyses have been performed, the following information should be provided: the name of the statistical test used, the n number for each analysis, the comparisons of interest, the alpha level and the actual P-value for each test. It should be clear which statistical test was used to generate every P-value. Error bars on graphs should be clearly labeled, and it should be stated whether the number following the ± sign is a standard deviation or a standard error. The word ‘significant’ should only be used when referring to statistically significant results, and should be accompanied by the relevant P-value. Significance indicators should be used on graphs and tables, and should be described in the figure or table legend, clearly indicating which groups are being compared.

Please note that Figure legends are not expected to contain information already described in Materials and methods, except for image-specific information, for example, for microscopy, mention the type of image, e.g., fluorescence and the original magnification if scale bars are not used. Legends should provide information concerning what is shown in the figure(s)/figure parts. The x- and y-axes of the graphs must be clearly explained in the legends, and when P-values are provided to indicate probability, the comparison to which these P-values refer must be clearly stated.

If cell lines are used, authors are strongly encouraged to include the following information in the materials and methods section of their manuscript: i) Confirm that mycoplasma testing has been done for the cell lines used; ii) confirm that the cell lines used have been authenticated and state what method was used for the authentication; and iii) provide the source, supplier and, if available, catalogue number of all specific cell lines used in the study. The authors are strongly encouraged to submit a detailed methodology stating the maintenance and culture of cell lines according to international guidelines on good cell culture practice (fundamental techniques, mycoplasma contamination, passage number, etc.). Furthermore, information regarding misidentified or cross-contaminated cell lines must be provided and cross-checked from the International Cell Line Authentication Committee and ExPASy Cellosaurus databases in order to exclude their contamination with other cell lines or their incorrect identification. If a cell line has been previously reported to be contaminated or misidentified, an STR profile of the cell line used in the study must be available for evaluation by the journal’s editor.

Results

Discussion

Acknowledgements

Funding

Availability of data and materials

Authors' contributions

Ethics approval and consent to participate

Patient consent for publication

Competing interests

Authors' information (optional)

References

Footnotes should not be used.

For Review articles:

Abstract. This section should have 150‐300 words, be continuous (not structured) and without reference numbers.

May have different sections and sub-headings according to the subject matter.

The main headings of the review should be summarized as a numbered Contents section immediately following the Abstract.

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